Gyles Brandreth is a former appeals chairman, chairman and currently vice-president of the National Playing Fields Association, now known as Fields in Trust:

In 1986 as chairman of the Barn Elms Protection Association, Gyles visited Sir Peter Scott to trigger the creation of what became the London Wetlands Centre:

Gyles has served on the appeals committee of what used to be called Action Research for the Crippled Child, now‎ He is the patron of PetSavers, a division of the British Small Animal Veterinary Association dedicated to improving the health of pets, providing vets with a better understanding of the illnesses that affect animals:

He is the founder of the Poetry Together project which encourages young people and older people to learn poetry together: He is a patron of the Polka Theatre for children in Wimbledon:, and an ambassador for the Old Sorting Office Arts Centre in Barnes: and for the Orange Tree Theatre in Richmond: 

Other charities he supports include:

He is a patron, president or vice-president of a number of societies, including:

In 1971, Gyles Brandreth founded the National Scrabble Championships. He is the president of the Association of British Scrabble Players: